Advanced Mass Spectrometry Suite

The advanced mass spectrometry suite hosts a MALDI accurate mass system and a SYNAPT G2-Si imaging mass spectrometer, allowing mass mapping of the surface of the sample.

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Detailed Description

SYNAPT G2-Si Imaging Mass Spectrometer

A mass spectrometer coupled to a powerful laser or DESI source. A laser or a solvent mix is directed to the surface of a plate which contains the sample. The sample is moved according to a pre-programmed raster and mass spectra are taken at each point. Post-processing of the continuous mass spectra allows the spatial resolution to be deconvoluted and an image of the differing masses extracted for each raster point.

  • Results are resolved in spatial coordinates in addition to masses
  • Can achieve very high mass for a MS system
  • Easy sample preparation
  • Rough surfaces can be analysed

Bruker AutoFlex MALDI-MS

This Matrix Assisted Laser Desorption Ionisation – Mass Spectrometer (MALDI-MS) is suitable for a wide range of samples from intact proteins to polymers. Matrix selections is key to obtain good results. It is a destructive technique. As the mass spectrometer is coupled to a powerful laser, it is capable of measuring high mass ranges that are not possible with a traditional ESI/APCI source.